Gate Neurosciences is focused on synapse biology that underlies CNS disease. The Boost discovery platform enhances our capabilities to address fundamental questions in synapse drug discovery and development.
Boost is a proprietary discovery platform created by combining Stanford biochemist Tom Südhof’s Nobel Prize-winning insights into synaptic function, formation and maintenance, with decades of practical knowledge in drug discovery and development. By harnessing uniquely optimized mature human iPSCs, we gain unprecedented insights into the formation of functional neuronal networks with proprietary analytics.
The Boost platform is capable of deep interrogation of synapse biology and pharmacology. Living culture of neurons and glial cells are uniquely engineered to unlock synaptogenic insights by giving unprecedented quantitative readouts on synapse function, structure and activity.
Gate Neurosciences is on the forefront of advancing cutting-edge synaptogenic treatments across high unmet need CNS diseases. By directly monitoring synaptic function with the Boost platform, we are accelerating novel target discovery, validation, clinical translation, and probability of success of our pipeline.
